The “acrosomal synapse”
نویسندگان
چکیده
منابع مشابه
Acrosomal Disruption in Sperm
"Capacitation" is a physiological event which alters sperm to permit rapid penetration through oocyte investments and fusion between gametes. Acrosomal "reaction," the physiological release of acrosomal contents, occurs after this facilitating process. In this study, acrosomal "disruption" of guinea pig and rat sperm was achieved in vitro by incubating sperm together with the follicular content...
متن کاملAcrosomal reaction of Thyone sperm. II. The kinetics and possible mechanism of acrosomal process elongation
Thyone sperm were induced to undergo the acrosomal reaction with a calcium ionophore A23187 in sea water containing 50 mM excess CaCl2, and the extension of the acrosomal process was recorded with high-resolution, differential interference contrast video microscopy at 60 fields/sec. The length of the acrosomal process was measured at 0.25-s intervals on nine sperm. When the data were plotted as...
متن کاملRegulatory mechanisms in acrosomal exocytosis.
Acrosomal exocytosis occurs after the binding of the spermatozoon to the zona pellucida of the oocyte via specific receptors. We suggest that the zona pellucida binds to at least two different receptors in the plasma membrane. One (R) is a Gi-coupled receptor that activates phospholipase C beta 1. The other (TK) is a tyrosine kinase receptor coupled to phospholipase C gamma. Binding to R would ...
متن کاملAcrosomal Reaction of Thyone Sperm
Structural changes inside the head of Thyone sperm undergoing the acrosomal reaction were followed with a high-resolution, differential interference contrast (DIC) video microscope . The beating sperm, adhering by their midpiece to the cover slip of a wedge perfusion chamber, were activated by a calcium ionophore (201uM A23187) suspended in sea water containing 50 mM excess CaC12. Before activa...
متن کاملThe Immunological Synapse T. Klemmensen: The Immunological Synapse
The induction of a proper adaptive immune response is dependent on the correct transfer of information between antigen-presenting cells (APCs) and antigen-specific T cells. Defects in information transfer may result in the development of diseases, e.g. immunodeficiencies and autoimmunity. A distinct 3-dimensional supramolecular structure at the T cell/APC interface has been suggested to be invo...
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ژورنال
عنوان ژورنال: Communicative & Integrative Biology
سال: 2010
ISSN: 1942-0889
DOI: 10.4161/cib.3.6.13137